A multinational report to characterise SARS-CoV-2 infection in people with cystic fibrosis

Rebecca Cosgriff, Susannah Ahern, Scott C. Bell, Keith Brownlee, Pierre Régis Burgel, Cass Byrnes, Harriet Corvol, Stephanie Y. Cheng, Alexander Elbert, Albert Faro, Christopher H. Goss, Vincent Gulmans, Bruce C. Marshall, Edward McKone, Peter G. Middleton, Rasa Ruseckaite, Anne L. Stephenson, Siobhán B. Carr

Research output: Contribution to journalArticlepeer-review

Abstract

Information is lacking on the clinical impact of the novel coronavirus, SARS-CoV-2, on people with cystic fibrosis (CF). Our aim was to characterise SARS-CoV-2 infection in people with cystic fibrosis. Methods: Anonymised data submitted by each participating country to their National CF Registry was reported using a standardised template, then collated and summarised. Results: 40 cases have been reported across 8 countries. Of the 40 cases, 31 (78%) were symptomatic for SARS-CoV-2 at presentation, with 24 (60%) having a fever. 70% have recovered, 30% remain unresolved at time of reporting, and no deaths have been submitted. Conclusions: This early report shows good recovery from SARS-CoV-2 in this heterogeneous CF cohort. The disease course does not seem to differ from the general population, but the current numbers are too small to draw firm conclusions and people with CF should continue to strictly follow public health advice to protect themselves from infection.

Original languageEnglish (US)
Pages (from-to)355-358
Number of pages4
JournalJournal of Cystic Fibrosis
Volume19
Issue number3
DOIs
StatePublished - May 2020

Keywords

  • Coronavirus
  • Cystic fibrosis
  • SARS-CoV-2

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine

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