A monoclonal antibody labels type II neurons of the spiral ganglion

Alice M. Berglund, David K. Ryugo

Research output: Contribution to journalArticlepeer-review

Abstract

Tissue from mature rat and cat cochleas was stained with basic dyes in order to distinguish between the cell bodies of type I and II spiral ganglion neurons. This same tissue was then stained with protargol, or processed immunocytochemically using a monoclonal neurofilament antibody, RT-97. Type II neurons were intensely stained, whereas type I neurons were not. We conclude that type II neurons can be clearly distinguished by their abundant neurofilament content.

Original languageEnglish (US)
Pages (from-to)327-332
Number of pages6
JournalBrain research
Volume383
Issue number1-2
DOIs
StatePublished - Sep 24 1986
Externally publishedYes

Keywords

  • Auditory system
  • Cochlea
  • Neurofilament
  • Primary afferent
  • RT-97
  • Sensory neuron

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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