A monoclonal antibody detecting a possible public specificity of the HLA‐C locus

Corazon L. Dejelo; William E. Braun; Andrea A. Zachary; Alan Smerglia; Linda Clark

doi:10.1111/j.1399-0039.1986.tb00461.x

A monoclonal antibody detecting a possible public specificity of the HLA‐C locus

Corazon L. Dejelo, William E. Braun, Andrea A. Zachary, Alan Smerglia, Linda Clark

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

An IgM monoclonal antibody (CC‐C1 11) was produced by fusing myeloma cell line SP2/08 with lymphocytes of a Balb/c mouse previously immunized with peripheral blood lymphocytes of an A2, Bw44, B27, Cw1, Cw7, DR5 donor. Reactivity of CC‐C1 11 on a lymphocyte panel of 172 unrelated donors and lysostripping and absorption experiments have shown that CC‐C1 11 recognizes an antigenic determinant common to HLA‐Cw1 and Cw3 positive lymphocytes.

Original language	English (US)
Pages (from-to)	57-62
Number of pages	6
Journal	Tissue Antigens
Volume	28
Issue number	1
DOIs	https://doi.org/10.1111/j.1399-0039.1986.tb00461.x
State	Published - Jul 1986

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Biochemistry
Genetics

Access to Document

10.1111/j.1399-0039.1986.tb00461.x

Cite this

@article{71cf072f2db24c6889a82fed972df012,

title = "A monoclonal antibody detecting a possible public specificity of the HLA‐C locus",

abstract = "An IgM monoclonal antibody (CC‐C1 11) was produced by fusing myeloma cell line SP2/08 with lymphocytes of a Balb/c mouse previously immunized with peripheral blood lymphocytes of an A2, Bw44, B27, Cw1, Cw7, DR5 donor. Reactivity of CC‐C1 11 on a lymphocyte panel of 172 unrelated donors and lysostripping and absorption experiments have shown that CC‐C1 11 recognizes an antigenic determinant common to HLA‐Cw1 and Cw3 positive lymphocytes.",

author = "Dejelo, {Corazon L.} and Braun, {William E.} and Zachary, {Andrea A.} and Alan Smerglia and Linda Clark",

year = "1986",

month = jul,

doi = "10.1111/j.1399-0039.1986.tb00461.x",

language = "English (US)",

volume = "28",

pages = "57--62",

journal = "HLA",

issn = "2059-2302",

publisher = "Wiley-Blackwell",

number = "1",

}

TY - JOUR

T1 - A monoclonal antibody detecting a possible public specificity of the HLA‐C locus

AU - Dejelo, Corazon L.

AU - Braun, William E.

AU - Zachary, Andrea A.

AU - Smerglia, Alan

AU - Clark, Linda

PY - 1986/7

Y1 - 1986/7

N2 - An IgM monoclonal antibody (CC‐C1 11) was produced by fusing myeloma cell line SP2/08 with lymphocytes of a Balb/c mouse previously immunized with peripheral blood lymphocytes of an A2, Bw44, B27, Cw1, Cw7, DR5 donor. Reactivity of CC‐C1 11 on a lymphocyte panel of 172 unrelated donors and lysostripping and absorption experiments have shown that CC‐C1 11 recognizes an antigenic determinant common to HLA‐Cw1 and Cw3 positive lymphocytes.

AB - An IgM monoclonal antibody (CC‐C1 11) was produced by fusing myeloma cell line SP2/08 with lymphocytes of a Balb/c mouse previously immunized with peripheral blood lymphocytes of an A2, Bw44, B27, Cw1, Cw7, DR5 donor. Reactivity of CC‐C1 11 on a lymphocyte panel of 172 unrelated donors and lysostripping and absorption experiments have shown that CC‐C1 11 recognizes an antigenic determinant common to HLA‐Cw1 and Cw3 positive lymphocytes.

UR - http://www.scopus.com/inward/record.url?scp=0022498304&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022498304&partnerID=8YFLogxK

U2 - 10.1111/j.1399-0039.1986.tb00461.x

DO - 10.1111/j.1399-0039.1986.tb00461.x

M3 - Article

C2 - 2428127

AN - SCOPUS:0022498304

SN - 2059-2302

VL - 28

SP - 57

EP - 62

JO - HLA

JF - HLA

IS - 1

ER -

A monoclonal antibody detecting a possible public specificity of the HLA‐C locus

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this