A molecular arms race: New insights into anti-CRISPR mechanisms

John Mallon, Scott Bailey

Research output: Contribution to journalShort survey

Abstract

Bacteria and phages are engaged in a molecular arms race, constantly coevolving to best each other. The crystal structure of the anti-CRISPR protein AcrF3 bound to Cas3, an essential component of CRISPR-based immunity, sheds light on how phages have found ways to suppress bacterial immunity.

Original languageEnglish (US)
Pages (from-to)765-766
Number of pages2
JournalNature Structural and Molecular Biology
Volume23
Issue number9
DOIs
StatePublished - Sep 1 2016

ASJC Scopus subject areas

  • Structural Biology
  • Medicine(all)
  • Molecular Biology

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