A molecular arms race: New insights into anti-CRISPR mechanisms

John Mallon; Scott Bailey

doi:10.1038/nsmb.3287

A molecular arms race: New insights into anti-CRISPR mechanisms

John Mallon, Scott Bailey

Bloomberg School of Public Health

Research output: Contribution to journal › Short survey › peer-review

5 Scopus citations

Abstract

Bacteria and phages are engaged in a molecular arms race, constantly coevolving to best each other. The crystal structure of the anti-CRISPR protein AcrF3 bound to Cas3, an essential component of CRISPR-based immunity, sheds light on how phages have found ways to suppress bacterial immunity.

Original language	English (US)
Pages (from-to)	765-766
Number of pages	2
Journal	Nature Structural and Molecular Biology
Volume	23
Issue number	9
DOIs	https://doi.org/10.1038/nsmb.3287
State	Published - Sep 1 2016

ASJC Scopus subject areas

Structural Biology
Molecular Biology

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10.1038/nsmb.3287

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abstract = "Bacteria and phages are engaged in a molecular arms race, constantly coevolving to best each other. The crystal structure of the anti-CRISPR protein AcrF3 bound to Cas3, an essential component of CRISPR-based immunity, sheds light on how phages have found ways to suppress bacterial immunity.",

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A molecular arms race: New insights into anti-CRISPR mechanisms

Abstract

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