A model of the coronary epicardial tree and intramyocardial circulation in normal and ischemic hearts

Dan Manor, Uri Dinnar, Samuel Sideman, Rafael Beyar

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A dynamic electrical analog RC model describing the coronary circulation was developed to relate the epicardial flow to the corresponding regional perfusion. The model is based on the aortic driving pressure, the left ventricular pressure, the dominant anatomy, and the geometry (length, diameter) of the epicardial coronary arteries. The myocardial zone supplied by each artery is represented as three compartmental resistances and two capacitances, changing with time as a function of transmural pressure. The intramyocardial pressure affects the circulation by means of the myocardial capacitances. The system has the ability to autoregulate in response to increased flow demand or severe stenosis. This model is also capable of accounting for fixed or dynamic stenoses in the epicardial arterial segments, and the corresponding collaterals which may be added as a function of time and stenosis severity. Pressures and flow rates at each arterial segment and myocardial compartment are calculated.

Original languageEnglish (US)
Title of host publicationComputers in Cardiology
PublisherPubl by IEEE
Pages247-250
Number of pages4
ISBN (Print)0818621141
StatePublished - Sep 1989
Externally publishedYes
EventProceedings - Computers in Cardiology - Jerusalem, Isr
Duration: Sep 19 1989Sep 22 1989

Other

OtherProceedings - Computers in Cardiology
CityJerusalem, Isr
Period9/19/899/22/89

ASJC Scopus subject areas

  • Software
  • Cardiology and Cardiovascular Medicine

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