@inproceedings{9d4ce1a8cc5b4467b7d9337002d9604a,
title = "A microtrap platform to investigate single cell mechanics",
abstract = "This paper reports a microfabricated microtrap platform for capture and micromechanics studies of single cells. Arrays of biocompatible glass-like three dimensional (3D) microtraps were engineered to capture single cells. By tuning lateral dimensions, thin film stress, and thickness of the traps, the extent of confinement and force on single cells could be tuned, allowing investigation of mechanics in 3D. The platform simultaneously allows optical and epifluorescence imaging of pre- and post-capture labeling, and parallel time lapse studies of cell dynamics induced by environmental changes.",
keywords = "3D, Biophysics, Cytoskeleton, Mechanotransduction, Micromechanics, Morphology, Nucleus",
author = "Qianru Jin and Gayatri Pahapale and Anil Bhatta and Aimee Dai and Lewis Romer and Gracias, {David H.}",
note = "Funding Information: The authors acknowledge funding from the NSF CMMI-1635443, and the JHU-SOM ACCM StAAR program. Publisher Copyright: {\textcopyright} 17CBMS-0001.; 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 ; Conference date: 22-10-2017 Through 26-10-2017",
year = "2020",
language = "English (US)",
series = "21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017",
publisher = "Chemical and Biological Microsystems Society",
pages = "908--909",
booktitle = "21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017",
}