A synthetic approach to both enantiomers of the secondary alcohols [Ph(CH2)nCH(OH)CXF2 (n=0-2) C6H13(CH2)nCH(OH)CFX2 (n=0 or 2) and CXF2CH(OH)CH2CO2Et [X=H or Cl], involving the stereoselective hydrolysis of ester derivatives, is described. The absolute configurations of these difluoromethylated or chlorodifluoromethylated molecules were determined.
ASJC Scopus subject areas
- Environmental Chemistry
- Physical and Theoretical Chemistry
- Organic Chemistry
- Inorganic Chemistry