A Method that Will Captivate U

Sophie Martin, Jeff Coller

Research output: Contribution to journalShort surveypeer-review

Abstract

In an age of next-generation sequencing, the ability to purify RNA transcripts has become a critical issue. In this issue, Duffy et al. (2015) improve on a pre-existing technique of RNA labeling and purification by 4-thiouridine tagging. By increasing the efficiency of RNA capture, this method will enhance the ability to study RNA dynamics, especially for transcripts normally inefficiently captured by previous methods. In an age of next-generation sequencing, the ability to purify RNA transcripts has become a critical issue. In this issue, Duffy et al. (2015) improve on a pre-existing technique of RNA labeling and purification by 4-thiouradine tagging. By increasing the efficiency of RNA capture, this method will enhance the ability to study RNA dynamics, especially for transcripts normally inefficiently captured by previous methods.

Original languageEnglish (US)
Pages (from-to)716-717
Number of pages2
JournalMolecular cell
Volume59
Issue number5
DOIs
StatePublished - Sep 3 2015
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

Fingerprint Dive into the research topics of 'A Method that Will Captivate U'. Together they form a unique fingerprint.

Cite this