TY - GEN
T1 - A method for real-time cortical oscillation detection and phase-locked stimulation
AU - Chen, L. Leon
AU - Madhavan, Radhika
AU - Rapoport, Benjamin I.
AU - Anderson, William S.
PY - 2011/12/26
Y1 - 2011/12/26
N2 - Neural oscillations are important features in a working central nervous system, facilitating efficient communication across large networks of neurons. To better study the role of these oscillations in various cognitive processes, and to be able to build clinical applications around them, accurate and precise estimations of the instantaneous frequency and phase are required. Here, we present methodology based on autoregressive modeling to accomplish this in real time. This allows the targeting of stimulation to a specific phase of a detected oscillation. Using intracranial EEG recorded from two patients performing a Sternberg memory task, we characterize our algorithm's phase-locking performance on physiologic theta oscillations.
AB - Neural oscillations are important features in a working central nervous system, facilitating efficient communication across large networks of neurons. To better study the role of these oscillations in various cognitive processes, and to be able to build clinical applications around them, accurate and precise estimations of the instantaneous frequency and phase are required. Here, we present methodology based on autoregressive modeling to accomplish this in real time. This allows the targeting of stimulation to a specific phase of a detected oscillation. Using intracranial EEG recorded from two patients performing a Sternberg memory task, we characterize our algorithm's phase-locking performance on physiologic theta oscillations.
UR - http://www.scopus.com/inward/record.url?scp=84862614872&partnerID=8YFLogxK
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U2 - 10.1109/IEMBS.2011.6090843
DO - 10.1109/IEMBS.2011.6090843
M3 - Conference contribution
C2 - 22254992
AN - SCOPUS:84862614872
SN - 9781424441211
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 3087
EP - 3090
BT - 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
T2 - 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
Y2 - 30 August 2011 through 3 September 2011
ER -