A method for functional magnetic resonance imaging of olfaction

N. Sobel, V. Prabhakaran, J. E. Desmond, G. H. Glover, E. V. Sullivan, J. D.E. Gabrieli

Research output: Contribution to journalArticle

Abstract

A method for generating olfactory stimuli for humans within a functional magnetic resonance imaging (fMRI) experimental design is described. The system incorporates a nasal-mask in which the change from odorant to no- odorant conditions occurs in less than 500 ms and is not accompanied by visual, auditory, tactile, or thermal cues. The mask provides an ordorant- free environment following prolonged ordorant presence. Specific imaging parameters that are conducive to the study of the human olfactory system are described. In a pilot study performed using these methods, the specific patterns of activation observed converged with published experimental and clinical findings.

Original languageEnglish (US)
Pages (from-to)115-123
Number of pages9
JournalJournal of Neuroscience Methods
Volume78
Issue number1-2
DOIs
StatePublished - Dec 30 1997
Externally publishedYes

Keywords

  • Functional magnetic resonance imaging
  • Human brain imaging
  • Odor perception
  • Olfaction
  • Olfactometer
  • Trigeminal
  • fMRI

ASJC Scopus subject areas

  • Neuroscience(all)

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  • Cite this

    Sobel, N., Prabhakaran, V., Desmond, J. E., Glover, G. H., Sullivan, E. V., & Gabrieli, J. D. E. (1997). A method for functional magnetic resonance imaging of olfaction. Journal of Neuroscience Methods, 78(1-2), 115-123. https://doi.org/10.1016/S0165-0270(97)00140-4