A marker chromosome in post-transplant bone marrow

Laura Morsberger, Kerry Powell, Yi Ning

Research output: Contribution to journalArticlepeer-review


Detection of small supernumerary marker chromosomes in karyotype analysis represents a diagnostic challenge. While such markers are usually detected during cytogenetic studies of constitutional chromosome abnormalities, they have also been found in specimens submitted from patients with acquired malignancies. We report here the detection of a marker chromosome in a bone marrow specimen from a patient who received a bone marrow transplantation. We discuss the importance of proper characterization and interpretation of marker chromosomes in clinical practice.

Original languageEnglish (US)
Article number42
JournalMolecular Cytogenetics
Issue number1
StatePublished - Jun 1 2016


  • Bone marrow transplantation
  • FISH
  • Isodicentric chromosomes
  • Marker chromosomes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Genetics
  • Genetics(clinical)
  • Biochemistry, medical


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