A longitudinal study of speech fluency in aphasia: CT correlates of recovery and persistent nonfluency

David S. Knopman, Ola A. Selnes, Nancy Niccum, Alan B. Rubens, Douglas Yock, David Larson

Research output: Contribution to journalArticlepeer-review

Abstract

The anatomic correlates of speech fluency were studied in 54 right-handed patients with aphasia due to stroke. Speech fluency was assessed at 1 month postonset and then monthly for 5 months. CTs obtained at 5 months postonset were used for lesion localization and volume determination. Persistent nonfluency was associated with lesions in the rolandic cortical region and underlying white matter. Recovery from nonfluency occurred in 6 of 27 patients. Lesions in these six patients were less extensive than lesions in patients with persistent nonfluency. Patients who were fluent by 1 month lacked extensive rolandic lesions.

Original languageEnglish (US)
Pages (from-to)1170-1178
Number of pages9
JournalNeurology
Volume33
Issue number9
DOIs
StatePublished - Sep 1983

ASJC Scopus subject areas

  • Clinical Neurology

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