A lock on phosphotyrosine signaling

Kathryn E. Muratore, Philip A. Cole

Research output: Contribution to journalArticle

Abstract

Protein phosphorylation plays a major role in cell signaling and human disease, so understanding the effects of tyrosine phosphorylation on protein structure and function is an area of intense investigation. A new technique allows site-specific incorporation of a nonhydrolyzable phosphotyrosine analogue into recombinant proteins, providing a new strategy for research in this important area.

Original languageEnglish (US)
Pages (from-to)454-456
Number of pages3
JournalACS Chemical Biology
Volume2
Issue number7
DOIs
StatePublished - Jul 2007

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Phosphotyrosine
Phosphorylation
Cell signaling
Recombinant Proteins
Tyrosine
Proteins
Research

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine

Cite this

A lock on phosphotyrosine signaling. / Muratore, Kathryn E.; Cole, Philip A.

In: ACS Chemical Biology, Vol. 2, No. 7, 07.2007, p. 454-456.

Research output: Contribution to journalArticle

Muratore, KE & Cole, PA 2007, 'A lock on phosphotyrosine signaling', ACS Chemical Biology, vol. 2, no. 7, pp. 454-456. https://doi.org/10.1021/cb7001285
Muratore, Kathryn E. ; Cole, Philip A. / A lock on phosphotyrosine signaling. In: ACS Chemical Biology. 2007 ; Vol. 2, No. 7. pp. 454-456.
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