Abstract
Diabetic retinopathy (DR) is a complication of diabetes affecting up o 80% of all diabetic patients. DR can lead to blindness and reduced quality of life. Some authors have hypothesized that changes in the flow dynamics associated with DR as well as changes in retinal oxygenation can lead to macular edema. Measurements of oxygen saturation in the retina could help understand the real mechanisms behind this condition. We present a novel spectroscopic imaging device to measure oxygen saturation in the retina. Our system uses a lenslet array to spatially and spectrocopically divide a fundus image. A three wavelengths algorithm is used to calculate oxygen saturation in small vessels. Only wavelengths in the 500 - 580 nm range are considered in order to minimize the wavelength dependence of the scattering from erythrocytes. Preliminary testing on healthy subjects showed values of oxygen saturation comparable to the one reported in the literature.
Original language | English (US) |
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Title of host publication | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
Volume | 6426 |
DOIs | |
State | Published - 2007 |
Externally published | Yes |
Event | Ophthalmic Technologies XVII - San Jose, CA, United States Duration: Jan 20 2007 → Jan 23 2007 |
Other
Other | Ophthalmic Technologies XVII |
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Country/Territory | United States |
City | San Jose, CA |
Period | 1/20/07 → 1/23/07 |
Keywords
- Diabetic retinopathy
- Lenslet
- Oximetry
ASJC Scopus subject areas
- Engineering(all)