Abstract
Ion channels, both ligand- And voltage-gated, play fundamental roles in many physiologic processes. Alteration in ion channel function underlies numerous pathologies, including hypertension, diabetes, chronic pain, epilepsy, certain cancers, and neuromuscular diseases. In addition, an increasing number of inherited and de novo ion channel mutations have been shown to contribute to disease states. Ion channels are thus a major class of pharmacotherapeutic targets.
Original language | English (US) |
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Pages (from-to) | 286-287 |
Number of pages | 2 |
Journal | Molecular Pharmacology |
Volume | 90 |
Issue number | 3 |
DOIs | |
State | Published - Sep 1 2016 |
Externally published | Yes |
ASJC Scopus subject areas
- General Medicine
- Molecular Medicine
- Pharmacology