A Kinase Gets Caspases into Shape

Denise J. Montell

Research output: Contribution to journalShort survey

Abstract

Two new papers (Kuranaga et al., 2006; Oshima et al., 2006) describe a previously uncharacterized Drosophila kinase (DmIKKε) that regulates the abundance of DIAP1, a protein best known for its ability to inhibit apoptosis. However, DmIKKε-mediated degradation of DIAP1 does not regulate apoptosis as might be predicted but instead regulates actin dynamics, cell morphology, and the differentiation of sensory organ precursor cells.

Original languageEnglish (US)
Pages (from-to)450-452
Number of pages3
JournalCell
Volume126
Issue number3
DOIs
StatePublished - Aug 4 2006

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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