A history of orthotopic heart transplantation

Trip J. Meine, Stuart D. Russell

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


Orthotopic human heart transplantation today is performed at more than 150 U.S. centers, and the average survival is more than 10 years. Its prevalence and success, however, belies the fact that just 40 years ago, no one had ever attempted the procedure in humans and that the procedure seemed destined for failure just a year after the first transplant. This article reviews the history of orthotopic heart transplantation, beginning with ancient Greek legends and culminating in modern successes.

Original languageEnglish (US)
Pages (from-to)190-196
Number of pages7
JournalCardiology in Review
Issue number4
StatePublished - Jul 1 2005


  • Cardiac surgery
  • Cardiology
  • Heart transplantation
  • History of medicine

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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