A graphical approach for presenting linkage results from a genomic screen

Elizabeth W. Pugh, Diptasri M. Mandal, Alexander F. Wilson

Research output: Contribution to journalArticle

Abstract

Initially, a sib‐pair linkage analysis was performed between the marker loci and six untransformed variables. Results from several variations of this initial analysis were compared using a graphical approach (P‐plots) to simplify presentation. When results were compared to the generating model, most of the aspects of the generating model were recovered, although we did not find evidence of the polygenic component shared by Q2 and Q3, or evidence of linkage between MG4 and Q4 at the 0.01 level. © 1995 Wiley‐Liss, Inc.

Original languageEnglish (US)
Pages (from-to)807-812
Number of pages6
JournalGenetic epidemiology
Volume12
Issue number6
DOIs
StatePublished - 1995

Keywords

  • P‐plots
  • sib‐pair linkage analysis
  • simulation

ASJC Scopus subject areas

  • Epidemiology
  • Genetics(clinical)

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