A framework for diagnosing and classifying intensive care unit-acquired weakness

Robert D. Stevens; Scott A. Marshall; David R. Cornblath; Ahmet Hoke; Dale M. Needham; Bernard De Jonghe; Naeem A. Ali; Tarek Sharshar

doi:10.1097/CCM.0b013e3181b6ef67

A framework for diagnosing and classifying intensive care unit-acquired weakness

Robert D. Stevens, Scott A. Marshall, David R. Cornblath, Ahmet Hoke, Dale M. Needham, Bernard De Jonghe, Naeem A. Ali, Tarek Sharshar

School of Medicine

Research output: Contribution to journal › Article › peer-review

272 Scopus citations

Abstract

Neuromuscular dysfunction is prevalent in critically ill patients, is associated with worse short-term outcomes, and is a determinant of long-term disability in intensive care unit survivors. Diagnosis is made with the help of clinical, electrophysiological, and morphological observations; however, the lack of a consistent nomenclature remains a barrier to research. We propose a simple framework for diagnosing and classifying neuro-muscular disorders acquired in critical illness.

Original language	English (US)
Pages (from-to)	S299-S308
Journal	Critical care medicine
Volume	37
Issue number	SUPPL. 10
DOIs	https://doi.org/10.1097/CCM.0b013e3181b6ef67
State	Published - Oct 2009

Keywords

Critical illness myopathy
Critical illness neuromyopathy
Critical illness polyneuropathy
Direct muscle stimulation
Electromyogram
Intensive care unit-acquired paresis
Intensive care unit-acquired weakness
Nerve conduction studies
Prolonged neuromuscular blockade

ASJC Scopus subject areas

Critical Care and Intensive Care Medicine

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10.1097/CCM.0b013e3181b6ef67

Cite this

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title = "A framework for diagnosing and classifying intensive care unit-acquired weakness",

abstract = "Neuromuscular dysfunction is prevalent in critically ill patients, is associated with worse short-term outcomes, and is a determinant of long-term disability in intensive care unit survivors. Diagnosis is made with the help of clinical, electrophysiological, and morphological observations; however, the lack of a consistent nomenclature remains a barrier to research. We propose a simple framework for diagnosing and classifying neuro-muscular disorders acquired in critical illness.",

keywords = "Critical illness myopathy, Critical illness neuromyopathy, Critical illness polyneuropathy, Direct muscle stimulation, Electromyogram, Intensive care unit-acquired paresis, Intensive care unit-acquired weakness, Nerve conduction studies, Prolonged neuromuscular blockade",

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T1 - A framework for diagnosing and classifying intensive care unit-acquired weakness

AU - Stevens, Robert D.

AU - Marshall, Scott A.

AU - Cornblath, David R.

AU - Hoke, Ahmet

AU - Needham, Dale M.

AU - De Jonghe, Bernard

AU - Ali, Naeem A.

AU - Sharshar, Tarek

PY - 2009/10

Y1 - 2009/10

N2 - Neuromuscular dysfunction is prevalent in critically ill patients, is associated with worse short-term outcomes, and is a determinant of long-term disability in intensive care unit survivors. Diagnosis is made with the help of clinical, electrophysiological, and morphological observations; however, the lack of a consistent nomenclature remains a barrier to research. We propose a simple framework for diagnosing and classifying neuro-muscular disorders acquired in critical illness.

AB - Neuromuscular dysfunction is prevalent in critically ill patients, is associated with worse short-term outcomes, and is a determinant of long-term disability in intensive care unit survivors. Diagnosis is made with the help of clinical, electrophysiological, and morphological observations; however, the lack of a consistent nomenclature remains a barrier to research. We propose a simple framework for diagnosing and classifying neuro-muscular disorders acquired in critical illness.

KW - Critical illness myopathy

KW - Critical illness neuromyopathy

KW - Critical illness polyneuropathy

KW - Direct muscle stimulation

KW - Electromyogram

KW - Intensive care unit-acquired paresis

KW - Intensive care unit-acquired weakness

KW - Nerve conduction studies

KW - Prolonged neuromuscular blockade

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ER -

A framework for diagnosing and classifying intensive care unit-acquired weakness

Abstract

Keywords

ASJC Scopus subject areas

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