A framework for diagnosing and classifying intensive care unit-acquired weakness

Robert D. Stevens, Scott A. Marshall, David R. Cornblath, Ahmet Hoke, Dale M. Needham, Bernard De Jonghe, Naeem A. Ali, Tarek Sharshar

Research output: Contribution to journalArticlepeer-review

272 Scopus citations


Neuromuscular dysfunction is prevalent in critically ill patients, is associated with worse short-term outcomes, and is a determinant of long-term disability in intensive care unit survivors. Diagnosis is made with the help of clinical, electrophysiological, and morphological observations; however, the lack of a consistent nomenclature remains a barrier to research. We propose a simple framework for diagnosing and classifying neuro-muscular disorders acquired in critical illness.

Original languageEnglish (US)
Pages (from-to)S299-S308
JournalCritical care medicine
Issue numberSUPPL. 10
StatePublished - Oct 2009


  • Critical illness myopathy
  • Critical illness neuromyopathy
  • Critical illness polyneuropathy
  • Direct muscle stimulation
  • Electromyogram
  • Intensive care unit-acquired paresis
  • Intensive care unit-acquired weakness
  • Nerve conduction studies
  • Prolonged neuromuscular blockade

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine


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