A fast reconstruction algorithm for fluorescence diffusion optical tomography

Xiaolei Song, Jing Bai, Xiaoyun Xiong, Zhaotian Zhang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Fluorescence Optical Diffusion Tomography (FODT) is considered as one of the most promising ways for non-invasive molecular-based Imaging. Many reconstructed approaches to FODT utilize iterative methods for data inversion. However, they are regarded as being time-consuming and far from meeting the real-time imaging requests. In this work, a fast pre-iteration algorithm based on the generalized inverse is established, which divides the image reconstruction into two steps that are off-line pre-iteration and on-line one-step reconstruction. In the pre-iteration step for obtaining the approximation of generalized inverse, a second order iterative format is employed to accelerate the convergence. Simulation based on the linear diffusion model shows that the distribution of fluorescent yield can be well estimated by this algorithm with second-order iteration. And the reconstructed speed is remarkably increased. Time-efficiency of this method will potentially promote the development of real-time imaging and the dynamic monitoring of molecular activity.

Original languageEnglish (US)
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Pages1476-1479
Number of pages4
Volume7 VOLS
StatePublished - 2005
Externally publishedYes
Event2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005 - Shanghai, China
Duration: Sep 1 2005Sep 4 2005

Other

Other2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005
CountryChina
CityShanghai
Period9/1/059/4/05

Fingerprint

Optical tomography
Fluorescence
Imaging techniques
Tomography
Iterative methods
Image reconstruction
Monitoring

ASJC Scopus subject areas

  • Bioengineering

Cite this

Song, X., Bai, J., Xiong, X., & Zhang, Z. (2005). A fast reconstruction algorithm for fluorescence diffusion optical tomography. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (Vol. 7 VOLS, pp. 1476-1479). [1616710]

A fast reconstruction algorithm for fluorescence diffusion optical tomography. / Song, Xiaolei; Bai, Jing; Xiong, Xiaoyun; Zhang, Zhaotian.

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 7 VOLS 2005. p. 1476-1479 1616710.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Song, X, Bai, J, Xiong, X & Zhang, Z 2005, A fast reconstruction algorithm for fluorescence diffusion optical tomography. in Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. vol. 7 VOLS, 1616710, pp. 1476-1479, 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005, Shanghai, China, 9/1/05.
Song X, Bai J, Xiong X, Zhang Z. A fast reconstruction algorithm for fluorescence diffusion optical tomography. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 7 VOLS. 2005. p. 1476-1479. 1616710
Song, Xiaolei ; Bai, Jing ; Xiong, Xiaoyun ; Zhang, Zhaotian. / A fast reconstruction algorithm for fluorescence diffusion optical tomography. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 7 VOLS 2005. pp. 1476-1479
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