Abstract
Nineteen children with atopic airway disease who had a demonstrable post-exercise decrease in forced expiratory volume in one second (FEV1) using a standardized stress on a cycloergometer were treated with disodium cromoglycate (cromolyn sodium) in a double blind crossover study with a placebo control. Significant reduction of post-exercise bronchospasm was obtained by a single dose of 20 mg. of the drug inhaled one hour before exercise; the effect of the single dose was enhanced if preceded by 3 weeks of daily medication. No side effects were detected during the prolonged use of the drug. The significance of cromolyn's effect on the phenomenon is discussed.
Original language | English (US) |
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Pages (from-to) | 57-63 |
Number of pages | 7 |
Journal | The Journal of allergy and clinical immunology |
Volume | 50 |
Issue number | 1 |
DOIs | |
State | Published - Jul 1972 |
Externally published | Yes |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology