A double-blind randomized trial of fish oil to lower triglycerides and improve cardiometabolic risk in adolescents

Samuel S. Gidding, Carol Prospero, Jobayer Hossain, Frances Zappalla, Prabhakaran Balagopal, Bonita Falkner, Peter Kwiterovich

Research output: Contribution to journalArticle

Abstract

Objectives To determine the efficacy of 4 g/day fish oil to lower triglycerides and impact lipoprotein particles, inflammation, insulin resistance, coagulation, and thrombosis. Study design Participants (n = 42, age 14 ± 2 years) with hypertriglyceridemia and low-density lipoprotein (LDL) cholesterol P >.05); no other group differences were seen. Conclusions In children, fish oil (4 g/day) lowers triglycerides slightly and may have an antithrombotic effect but has no effect on LDL particles.

Original languageEnglish (US)
JournalJournal of Pediatrics
Volume165
Issue number3
DOIs
StatePublished - 2014

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Fish Oils
Triglycerides
Hypertriglyceridemia
LDL Lipoproteins
LDL Cholesterol
Lipoproteins
Insulin Resistance
Thrombosis
Inflammation

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Medicine(all)

Cite this

Gidding, S. S., Prospero, C., Hossain, J., Zappalla, F., Balagopal, P., Falkner, B., & Kwiterovich, P. (2014). A double-blind randomized trial of fish oil to lower triglycerides and improve cardiometabolic risk in adolescents. Journal of Pediatrics, 165(3). https://doi.org/10.1016/j.jpeds.2014.05.039

A double-blind randomized trial of fish oil to lower triglycerides and improve cardiometabolic risk in adolescents. / Gidding, Samuel S.; Prospero, Carol; Hossain, Jobayer; Zappalla, Frances; Balagopal, Prabhakaran; Falkner, Bonita; Kwiterovich, Peter.

In: Journal of Pediatrics, Vol. 165, No. 3, 2014.

Research output: Contribution to journalArticle

Gidding, SS, Prospero, C, Hossain, J, Zappalla, F, Balagopal, P, Falkner, B & Kwiterovich, P 2014, 'A double-blind randomized trial of fish oil to lower triglycerides and improve cardiometabolic risk in adolescents', Journal of Pediatrics, vol. 165, no. 3. https://doi.org/10.1016/j.jpeds.2014.05.039
Gidding, Samuel S. ; Prospero, Carol ; Hossain, Jobayer ; Zappalla, Frances ; Balagopal, Prabhakaran ; Falkner, Bonita ; Kwiterovich, Peter. / A double-blind randomized trial of fish oil to lower triglycerides and improve cardiometabolic risk in adolescents. In: Journal of Pediatrics. 2014 ; Vol. 165, No. 3.
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