A CRISPR way to engineer the human genome

Sivaprakash Ramalingam, Narayana Annaluru, Srinivasan Chandrasegaran

Research output: Contribution to journalArticle

Abstract

RNA-guided genome engineering based on the type II prokaryotic CRISPR/Cas system provides an effi cient and versatile method for targeted manipulation of mammalian genomes.

Original languageEnglish (US)
Article number107
JournalGenome Biology
Volume14
Issue number2
DOIs
StatePublished - Feb 26 2013

Fingerprint

Clustered Regularly Interspaced Short Palindromic Repeats
Human Genome
engineers
CRISPR-Cas Systems
genome
Genome
RNA
engineering
methodology

ASJC Scopus subject areas

  • Cell Biology
  • Ecology, Evolution, Behavior and Systematics
  • Genetics
  • Medicine(all)

Cite this

A CRISPR way to engineer the human genome. / Ramalingam, Sivaprakash; Annaluru, Narayana; Chandrasegaran, Srinivasan.

In: Genome Biology, Vol. 14, No. 2, 107, 26.02.2013.

Research output: Contribution to journalArticle

Ramalingam, Sivaprakash ; Annaluru, Narayana ; Chandrasegaran, Srinivasan. / A CRISPR way to engineer the human genome. In: Genome Biology. 2013 ; Vol. 14, No. 2.
@article{000824e61d794420bd5d9c100d1f6966,
title = "A CRISPR way to engineer the human genome",
abstract = "RNA-guided genome engineering based on the type II prokaryotic CRISPR/Cas system provides an effi cient and versatile method for targeted manipulation of mammalian genomes.",
author = "Sivaprakash Ramalingam and Narayana Annaluru and Srinivasan Chandrasegaran",
year = "2013",
month = "2",
day = "26",
doi = "10.1186/gb-2013-14-2-107",
language = "English (US)",
volume = "14",
journal = "Genome Biology",
issn = "1474-7596",
publisher = "BioMed Central",
number = "2",

}

TY - JOUR

T1 - A CRISPR way to engineer the human genome

AU - Ramalingam, Sivaprakash

AU - Annaluru, Narayana

AU - Chandrasegaran, Srinivasan

PY - 2013/2/26

Y1 - 2013/2/26

N2 - RNA-guided genome engineering based on the type II prokaryotic CRISPR/Cas system provides an effi cient and versatile method for targeted manipulation of mammalian genomes.

AB - RNA-guided genome engineering based on the type II prokaryotic CRISPR/Cas system provides an effi cient and versatile method for targeted manipulation of mammalian genomes.

UR - http://www.scopus.com/inward/record.url?scp=84874220668&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84874220668&partnerID=8YFLogxK

U2 - 10.1186/gb-2013-14-2-107

DO - 10.1186/gb-2013-14-2-107

M3 - Article

C2 - 23448668

AN - SCOPUS:84874220668

VL - 14

JO - Genome Biology

JF - Genome Biology

SN - 1474-7596

IS - 2

M1 - 107

ER -