Lansang M A (Liver Study Group, University of the Philippines, College of Medicine, Manila, Philippines), Domingo E, Lingao A and West S. A cost-effectiveness analysis of a simple micromethod for hepatitis B screening in hepatitis B virus control programmes. International Journal of Epidemiology 1989, 18 (Suppl 2): S38-S43. We developed a simple micromethod for identifying mothers who are most likely to transmit hepatitis B infection to their infants, using reverse passive haemagglutination for detecting HBsAg (hepatitis B surface antigen) in capillary blood. This screening method was evaluated against other strategies for hepatitis B control by means of decision- and cost-effectiveness analyses. The micromethod was shown to be cost-effective when the cost of hepatitis B vaccine was high. However, with increasingly reduced costs of the vaccine, it may have a limited role in a programme of mass immunization for hepatitis B.
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