A correlative study of papanicolaou smear, fluorescent antibody, and culture for the diagnosis of chlamydia trachomatis

Michael R. Spence, Marguerite Barbacci, Elizabeth Kappus, Thomas Quinn

Research output: Contribution to journalArticle

Abstract

A prospective study of 300 patients undergoing therapeutic termination of pregnancy was conducted. A Papanicolaou smear was obtained and a clinical evaluation of the cervix was made. Specimens from the cervix were examined by both direct fluorescent antibody and culture techniques for the presence of Chlamydia trachomatis. The presence of inflammation on Papanicolaou smear could be correlated with C trachomatis isolation. Papanicolaou smear findings consistent with C trachomatis lacked both sensitivity and specificity when compared with direct fluorescent antibody and/or culture techniques. A correlation was found between the clinical diagnosis of cervicitis and C trachomatis. This interrelationship was absent when the component findings of cervicitis (ectopy, friability, and purulent mucus) were examined independently.

Original languageEnglish (US)
Pages (from-to)691-695
Number of pages5
JournalObstetrics and gynecology
Volume68
Issue number5
StatePublished - Nov 1986

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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