A corneal micropocket assay for angiogenesis in the rat eye is described in detail. With our test system, a partially purified, low molecular-weight endothelial cell growth stimulatory factor isolated from the Walker 256 rat carcinosarcoma is demonstrated to have potent angiogenic activity in vivo. The advantages and applications of our rat corneal assay are discussed.
|Original language||English (US)|
|Number of pages||4|
|Journal||Investigative Ophthalmology and Visual Science|
|State||Published - Nov 13 1981|
ASJC Scopus subject areas
- Sensory Systems
- Cellular and Molecular Neuroscience