A convenient method for the synthesis of unsymmetrical 3,4-disubstituted pyrroles

Patrick W. Shum, Alan P. Kozikowski

Research output: Contribution to journalArticle

Abstract

A simplified procedure for the synthesis of 3,4-dibromo-1-[tris(1-methylethyl)silyl]-1H-pyrrole (2) is described together with its sequential halogen-metal exchange chemistry to afford 3,4-disubstituted pyrroles.

Original languageEnglish (US)
Pages (from-to)6785-6788
Number of pages4
JournalTetrahedron Letters
Volume31
Issue number47
DOIs
StatePublished - 1990

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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