A convenient method for the synthesis of unsymmetrical 3,4-disubstituted pyrroles

Patrick W. Shum, Alan P. Kozikowski

Research output: Contribution to journalArticle

Abstract

A simplified procedure for the synthesis of 3,4-dibromo-1-[tris(1-methylethyl)silyl]-1H-pyrrole (2) is described together with its sequential halogen-metal exchange chemistry to afford 3,4-disubstituted pyrroles.

Original languageEnglish (US)
Pages (from-to)6785-6788
Number of pages4
JournalTetrahedron Letters
Volume31
Issue number47
DOIs
StatePublished - 1990
Externally publishedYes

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Pyrroles
Halogens
Metals

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

A convenient method for the synthesis of unsymmetrical 3,4-disubstituted pyrroles. / W. Shum, Patrick; Kozikowski, Alan P.

In: Tetrahedron Letters, Vol. 31, No. 47, 1990, p. 6785-6788.

Research output: Contribution to journalArticle

W. Shum, Patrick ; Kozikowski, Alan P. / A convenient method for the synthesis of unsymmetrical 3,4-disubstituted pyrroles. In: Tetrahedron Letters. 1990 ; Vol. 31, No. 47. pp. 6785-6788.
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