A convenient method for the preparation of mono N-alkylated cyclams and cyclens in high yields

Cong Li, Wing Tak Wong

Research output: Contribution to journalArticle

Abstract

Selective and high yield synthesis of mono N-substituted derivatives of cyclam and cyclen can be achieved by using a direct and general synthetic method with very mild reaction conditions.

Original languageEnglish (US)
Pages (from-to)3217-3220
Number of pages4
JournalTetrahedron Letters
Volume43
Issue number17
DOIs
StatePublished - Apr 22 2002
Externally publishedYes

Keywords

  • Alkylation
  • Cyclam
  • Cyclen
  • Synthesis

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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