A convenient method for the preparation of mono N-alkylated cyclams and cyclens in high yields

Cong Li; Wing Tak Wong

doi:10.1016/S0040-4039(02)00497-5

A convenient method for the preparation of mono N-alkylated cyclams and cyclens in high yields

Cong Li, Wing Tak Wong

Research output: Contribution to journal › Article › peer-review

56 Scopus citations

Abstract

Selective and high yield synthesis of mono N-substituted derivatives of cyclam and cyclen can be achieved by using a direct and general synthetic method with very mild reaction conditions.

Original language	English (US)
Pages (from-to)	3217-3220
Number of pages	4
Journal	Tetrahedron Letters
Volume	43
Issue number	17
DOIs	https://doi.org/10.1016/S0040-4039(02)00497-5
State	Published - Apr 22 2002
Externally published	Yes

Keywords

Alkylation
Cyclam
Cyclen
Synthesis

ASJC Scopus subject areas

Biochemistry
Organic Chemistry
Drug Discovery

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10.1016/S0040-4039(02)00497-5

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title = "A convenient method for the preparation of mono N-alkylated cyclams and cyclens in high yields",

abstract = "Selective and high yield synthesis of mono N-substituted derivatives of cyclam and cyclen can be achieved by using a direct and general synthetic method with very mild reaction conditions.",

keywords = "Alkylation, Cyclam, Cyclen, Synthesis",

author = "Cong Li and Wong, {Wing Tak}",

year = "2002",

month = apr,

day = "22",

doi = "10.1016/S0040-4039(02)00497-5",

language = "English (US)",

volume = "43",

pages = "3217--3220",

journal = "Tetrahedron Letters",

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T1 - A convenient method for the preparation of mono N-alkylated cyclams and cyclens in high yields

AU - Li, Cong

AU - Wong, Wing Tak

PY - 2002/4/22

Y1 - 2002/4/22

N2 - Selective and high yield synthesis of mono N-substituted derivatives of cyclam and cyclen can be achieved by using a direct and general synthetic method with very mild reaction conditions.

AB - Selective and high yield synthesis of mono N-substituted derivatives of cyclam and cyclen can be achieved by using a direct and general synthetic method with very mild reaction conditions.

KW - Alkylation

KW - Cyclam

KW - Cyclen

KW - Synthesis

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U2 - 10.1016/S0040-4039(02)00497-5

DO - 10.1016/S0040-4039(02)00497-5

M3 - Article

AN - SCOPUS:0037156457

SN - 0040-4039

VL - 43

SP - 3217

EP - 3220

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 17

ER -

A convenient method for the preparation of mono N-alkylated cyclams and cyclens in high yields

Abstract

Keywords

ASJC Scopus subject areas

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