A conference report on prenatal corticosteroid use in low- and middle-income countries

Elizabeth M. McClure, Joseph De Graft-Johnson, Alan H. Jobe, Steve Wall, Marge Koblinsky, Allisyn Moran, Linda L. Wright, Winifride Mwebesa, Marion Koso-Thomas, Robert L. Goldenberg

Research output: Contribution to journalArticlepeer-review


Objective: To evaluate the evidence for prenatal corticosteroid use in low- and middle-income countries and to make recommendations regarding implementation and further research. Methods: Studies and meta-analyses on prenatal corticosteroids relevant to low- and middle-income countries were identified and reviewed at the Maternal and Child Health Integrated Project (MCHIP) Antenatal Corticosteroid Conference held in Washington on October 19, 2010. Results: There is strong evidence regarding the effectiveness of prenatal corticosteroid use in hospitals in high- and middle-income countries, usually in settings with high-level newborn care. For births occurring in hospitals in low-income countries without high-level neonatal care or for births outside hospitals, no studies have been conducted to evaluate prenatal corticosteroid use. The efficacy and safety of prenatal corticosteroid use in these settings must be evaluated. Conclusions: The conference working group recommended expanding the use of prenatal corticosteroids in hospitals with high-level newborn care in low-income countries. For other low-income country settings, further research regarding efficacy and safety should precede the widespread introduction of prenatal corticosteroids.

Original languageEnglish (US)
Pages (from-to)215-219
Number of pages5
JournalInternational Journal of Gynecology and Obstetrics
Issue number3
StatePublished - Dec 2011
Externally publishedYes


  • Low-resource countries
  • Prenatal corticosteroids
  • Preterm birth

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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