TY - JOUR
T1 - A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease
AU - Jessen, Frank
AU - Amariglio, Rebecca E.
AU - Van Boxtel, Martin
AU - Breteler, Monique
AU - Ceccaldi, Mathieu
AU - Chételat, Gaël
AU - Dubois, Bruno
AU - Dufouil, Carole
AU - Ellis, Kathryn A.
AU - Van Der Flier, Wiesje M.
AU - Glodzik, Lidia
AU - Van Harten, Argonde C.
AU - De Leon, Mony J.
AU - McHugh, Pauline
AU - Mielke, Michelle M.
AU - Molinuevo, Jose Luis
AU - Mosconi, Lisa
AU - Osorio, Ricardo S.
AU - Perrotin, Audrey
AU - Petersen, Ronald C.
AU - Rabin, Laura A.
AU - Rami, Lorena
AU - Reisberg, Barry
AU - Rentz, Dorene M.
AU - Sachdev, Perminder S.
AU - De La Sayette, Vincent
AU - Saykin, Andrew J.
AU - Scheltens, Philip
AU - Shulman, Melanie B.
AU - Slavin, Melissa J.
AU - Sperling, Reisa A.
AU - Stewart, Robert
AU - Uspenskaya, Olga
AU - Vellas, Bruno
AU - Visser, Pieter Jelle
AU - Wagner, Michael
PY - 2014/11/1
Y1 - 2014/11/1
N2 - There is increasing evidence that subjective cognitive decline (SCD) in individuals with unimpaired performance on cognitive tests may represent the first symptomatic manifestation of Alzheimer's disease (AD). The research on SCD in early AD, however, is limited by the absence of common standards. The working group of the Subjective Cognitive Decline Initiative (SCD-I) addressed this deficiency by reaching consensus on terminology and on a conceptual framework for research on SCD in AD. In this publication, research criteria for SCD in pre-mild cognitive impairment (MCI) are presented. In addition, a list of core features proposed for reporting in SCD studies is provided, which will enable comparability of research across different settings. Finally, a set of features is presented, which in accordance with current knowledge, increases the likelihood of the presence of preclinical AD in individuals with SCD. This list is referred to as SCD plus.
AB - There is increasing evidence that subjective cognitive decline (SCD) in individuals with unimpaired performance on cognitive tests may represent the first symptomatic manifestation of Alzheimer's disease (AD). The research on SCD in early AD, however, is limited by the absence of common standards. The working group of the Subjective Cognitive Decline Initiative (SCD-I) addressed this deficiency by reaching consensus on terminology and on a conceptual framework for research on SCD in AD. In this publication, research criteria for SCD in pre-mild cognitive impairment (MCI) are presented. In addition, a list of core features proposed for reporting in SCD studies is provided, which will enable comparability of research across different settings. Finally, a set of features is presented, which in accordance with current knowledge, increases the likelihood of the presence of preclinical AD in individuals with SCD. This list is referred to as SCD plus.
KW - Alzheimer's disease
KW - Mild cognitive impairment
KW - Preclinical Alzheimer's disease
KW - Prodromal Alzheimer 's disease
KW - Research criteria
KW - Subjective cognitive decline
UR - http://www.scopus.com/inward/record.url?scp=84927176303&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84927176303&partnerID=8YFLogxK
U2 - 10.1016/j.jalz.2014.01.001
DO - 10.1016/j.jalz.2014.01.001
M3 - Article
C2 - 24798886
AN - SCOPUS:84927176303
SN - 1552-5260
VL - 10
SP - 844
EP - 852
JO - Alzheimer's and Dementia
JF - Alzheimer's and Dementia
IS - 6
ER -