Abstract
We address the problem of efficiently aligning a transcribed and spliced DNA sequence with a genomic sequence containing that gene, allowing for introns in the genomic sequence and a relatively small number of sequencing errors. A freely available computer program, described herein, solves the problem for a 100-kb genomic sequence in a few seconds on a workstation.
Original language | English (US) |
---|---|
Pages (from-to) | 967-974 |
Number of pages | 8 |
Journal | Genome research |
Volume | 8 |
Issue number | 9 |
DOIs | |
State | Published - Sep 1998 |
Externally published | Yes |
ASJC Scopus subject areas
- Genetics
- Genetics(clinical)