A computational study of the hemodynamics of bioprosthetic aortic valves with reduced leaflet motion

Shantanu Bailoor, Jung Hee Seo, Lakshmi Prasad Dasi, Stefano Schena, Rajat Mittal

Research output: Contribution to journalArticlepeer-review

Abstract

We employ a reduced degree-of-freedom aortic valve model to investigate the flow physics associated with early-stage reduced leaflet motion in bioprosthetic aortic valves. The model is coupled with a sharp-interface immersed boundary based incompressible flow solver to efficiently simulate the fluid–structure interaction. A total of 19 cases of flow through aortic valves with varying degrees of reduced leaflet motion (RLM) are considered. The characteristics of the aortic jet and the consequent aorta wall loading patterns are analyzed. Our results show that asymmetric RLM tilts the aortic jet and leads to large reverse and recirculating flow regions downstream from leaflets with restricted mobility. The changes in flow patterns increase wall pressure and shear stress fluctuations, and result in asymmetric oscillating shear on the aorta wall. These findings have implications for auscultation based diagnosis of this condition as well as the health of the aorta.

Original languageEnglish (US)
Article number110350
JournalJournal of Biomechanics
Volume120
DOIs
StatePublished - May 7 2021

Keywords

  • Fluid structure interaction
  • Immersed boundary method
  • Leaflet thrombosis
  • Reduced-order models
  • Transcatheter aortic valves

ASJC Scopus subject areas

  • Biophysics
  • Biomedical Engineering
  • Orthopedics and Sports Medicine
  • Rehabilitation

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