A comprehensive review of naloxone for the emergency physician

James M. Chamberlain; Bruce L. Klein

doi:10.1016/0735-6757(94)90033-7

A comprehensive review of naloxone for the emergency physician

James M. Chamberlain, Bruce L. Klein

Research output: Contribution to journal › Review article › peer-review

95 Scopus citations

Abstract

Naloxone has enjoyed long-standing success as a safe and effective opioid antagonist and has been invaluable in defining the role of endogenous opioid pathways in the response to pathological states such as sepsis and hypovolemia. We look forward to exciting research to further elucidate these pathways and to improve outcome by modulating the patient's physiological response to these stresses.

Original language	English (US)
Pages (from-to)	650-660
Number of pages	11
Journal	American Journal of Emergency Medicine
Volume	12
Issue number	6
DOIs	https://doi.org/10.1016/0735-6757(94)90033-7
State	Published - Nov 1994
Externally published	Yes

Keywords

Naloxone
opioid antagonists
opioids

ASJC Scopus subject areas

Emergency Medicine

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10.1016/0735-6757(94)90033-7

Cite this

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title = "A comprehensive review of naloxone for the emergency physician",

abstract = "Naloxone has enjoyed long-standing success as a safe and effective opioid antagonist and has been invaluable in defining the role of endogenous opioid pathways in the response to pathological states such as sepsis and hypovolemia. We look forward to exciting research to further elucidate these pathways and to improve outcome by modulating the patient's physiological response to these stresses.",

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AB - Naloxone has enjoyed long-standing success as a safe and effective opioid antagonist and has been invaluable in defining the role of endogenous opioid pathways in the response to pathological states such as sepsis and hypovolemia. We look forward to exciting research to further elucidate these pathways and to improve outcome by modulating the patient's physiological response to these stresses.

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KW - opioids

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A comprehensive review of naloxone for the emergency physician

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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