A compendium of proteins that interact with HIF-1α

Research output: Contribution to journalArticle

Abstract

Hypoxia-inducible factor 1 (HIF-1) is the founding member of a family of transcription factors that function as master regulators of oxygen homeostasis. HIF-1 is composed of an O2-regulated HIF-1α subunit and a constitutively expressed HIF-1β subunit. This review provides a compendium of proteins that interact with the HIF-1α subunit, many of which regulate HIF-1 activity in either an O2-dependent or O2-independent manner.

Original languageEnglish (US)
JournalExperimental Cell Research
DOIs
StateAccepted/In press - Mar 15 2017

Keywords

  • Oxygen biology
  • Transcriptional regulation

ASJC Scopus subject areas

  • Cell Biology

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