A comparison of the growth suppressive effect of cortisone, prednisone, and other adrenal cortical hormones

Thomas E. Van Metre, William A. Niermann, Lawrence J. Rosen

Research output: Contribution to journalArticle

Abstract

Normal linear growth was noted in all of thirteen children given sufficient cortisone over a period of six months or longer to suppress asthma. Linear growth suppression was noted in twelve of thirteen children given prednisone, five of nine given methylprednisolone, the two given fluprednisolone, and in the one given triamcinolone, when sufficent corticosteroid was given for a similar period of time to produce the same degree of suppression of asthma. Evidence is presented indicating that cortisone is about one fifth as potent as prednisone and one sixth as potent as methylprednisolone as a therapeutic agent in asthma, but only one tenth as potent as each as a growth inhibiting agent.

Original languageEnglish (US)
Pages (from-to)531-542
Number of pages12
JournalJournal of Allergy
Volume31
Issue number6
DOIs
StatePublished - Jan 1 1960

ASJC Scopus subject areas

  • Medicine(all)

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