A comparison of optimum detector spatial resolution in nuclear imaging based on statistical theory and on observer performance

An expression for the expected image of a spherical tumour in a uniform background was derived in terms of background thickness and concentration of radioactivity, the tumour size, depth and uptake ratio, the gamma -ray energy and the detector response function. Three models of human observer performance for tumour detection were developed from different signal-to-noise ratio measures based on the statistical theory of detection. The optimum detector spatial resolution predicted by each model was then compared to that obtained from an observer performance study in which the subjects viewed computer-simulated scintigrams.