TY - JOUR
T1 - A comparative study of the β-crystallins of four sub-mammalian species
AU - Zigler, J. Samuel
AU - Sidbury, J. B.
N1 - Funding Information:
As a result of considerable interest in the developmental aspects of lens biochemistry (see Polansky & Bennett, 1973; Brahma & Bours, 1972), the proteins of the amphibian lens have been better characterized Supported in part by NIH grants AM 06815 and EY 01607.
PY - 1976
Y1 - 1976
N2 - 1. 1. The β-crystallins from species representing the vertebrate classes Osteichthyes, Amphibia, Reptilia, and Aves have been isolated. 2. 2. Each of these species had two classes of β-crystallin (βH and βL) differing in molecular weight, but comprised in large part of identical polypeptides. 3. 3. Physico-chemical techniques were utilized to evaluate the structural similarity of the various purified β-crystallins to each other and to mammalian β-crystallins previously studied. 4. 4. Immunochemical data suggest that certain components of β-crystallin have been rigidly conserved during evolution while others have apparently evolved rapidly.
AB - 1. 1. The β-crystallins from species representing the vertebrate classes Osteichthyes, Amphibia, Reptilia, and Aves have been isolated. 2. 2. Each of these species had two classes of β-crystallin (βH and βL) differing in molecular weight, but comprised in large part of identical polypeptides. 3. 3. Physico-chemical techniques were utilized to evaluate the structural similarity of the various purified β-crystallins to each other and to mammalian β-crystallins previously studied. 4. 4. Immunochemical data suggest that certain components of β-crystallin have been rigidly conserved during evolution while others have apparently evolved rapidly.
UR - http://www.scopus.com/inward/record.url?scp=0017127219&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0017127219&partnerID=8YFLogxK
U2 - 10.1016/0305-0491(76)90166-8
DO - 10.1016/0305-0491(76)90166-8
M3 - Article
C2 - 820513
AN - SCOPUS:0017127219
SN - 0305-0491
VL - 55
SP - 19
EP - 24
JO - Comparative Biochemistry and Physiology -- Part B: Biochemistry and
JF - Comparative Biochemistry and Physiology -- Part B: Biochemistry and
IS - 1
ER -