TY - GEN
T1 - A CMOS neurostimulator with on-chip DAC calibration and charge balancing
AU - Greenwald, Elliot
AU - Chen, Cheng
AU - Thakor, Nitish
AU - Maier, Christoph
AU - Cauwenberghs, Gert
PY - 2013
Y1 - 2013
N2 - A multi-channel biphasic neural stimulator with on-chip DAC calibration and current matching capabilities is presented. Each channel consists of two sub-binary radix DACs, for the anodic and cathodic stimulation phases, and a wideswing high output impedance current source and sink. A single integrator is shared among channels and serves to calibrate DAC coefficients and to closely match the anodic and cathodic stimulation phases. After calibration, the differential non-linearity is bounded between +/- 0.5 LSBs at 8-bit resolution, and the two stimulation phases can be matched to better than 50 nA. We demonstrate operation with stimulation through a tungsten microelectrode in saline, and show stimulator induced modulation of neural activity in the cortex of a rat. Our novel architecture allows for blind self-calibration, amenable to implantable neural interfaces.
AB - A multi-channel biphasic neural stimulator with on-chip DAC calibration and current matching capabilities is presented. Each channel consists of two sub-binary radix DACs, for the anodic and cathodic stimulation phases, and a wideswing high output impedance current source and sink. A single integrator is shared among channels and serves to calibrate DAC coefficients and to closely match the anodic and cathodic stimulation phases. After calibration, the differential non-linearity is bounded between +/- 0.5 LSBs at 8-bit resolution, and the two stimulation phases can be matched to better than 50 nA. We demonstrate operation with stimulation through a tungsten microelectrode in saline, and show stimulator induced modulation of neural activity in the cortex of a rat. Our novel architecture allows for blind self-calibration, amenable to implantable neural interfaces.
UR - http://www.scopus.com/inward/record.url?scp=84893558229&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84893558229&partnerID=8YFLogxK
U2 - 10.1109/BioCAS.2013.6679646
DO - 10.1109/BioCAS.2013.6679646
M3 - Conference contribution
AN - SCOPUS:84893558229
SN - 9781479914715
T3 - 2013 IEEE Biomedical Circuits and Systems Conference, BioCAS 2013
SP - 89
EP - 92
BT - 2013 IEEE Biomedical Circuits and Systems Conference, BioCAS 2013
T2 - 2013 IEEE Biomedical Circuits and Systems Conference, BioCAS 2013
Y2 - 31 October 2013 through 2 November 2013
ER -