A CMOS neurostimulator with on-chip DAC calibration and charge balancing

Elliot Greenwald, Cheng Chen, Nitish Thakor, Christoph Maier, Gert Cauwenberghs

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A multi-channel biphasic neural stimulator with on-chip DAC calibration and current matching capabilities is presented. Each channel consists of two sub-binary radix DACs, for the anodic and cathodic stimulation phases, and a wideswing high output impedance current source and sink. A single integrator is shared among channels and serves to calibrate DAC coefficients and to closely match the anodic and cathodic stimulation phases. After calibration, the differential non-linearity is bounded between +/- 0.5 LSBs at 8-bit resolution, and the two stimulation phases can be matched to better than 50 nA. We demonstrate operation with stimulation through a tungsten microelectrode in saline, and show stimulator induced modulation of neural activity in the cortex of a rat. Our novel architecture allows for blind self-calibration, amenable to implantable neural interfaces.

Original languageEnglish (US)
Title of host publication2013 IEEE Biomedical Circuits and Systems Conference, BioCAS 2013
Pages89-92
Number of pages4
DOIs
StatePublished - Dec 1 2013
Event2013 IEEE Biomedical Circuits and Systems Conference, BioCAS 2013 - Rotterdam, Netherlands
Duration: Oct 31 2013Nov 2 2013

Publication series

Name2013 IEEE Biomedical Circuits and Systems Conference, BioCAS 2013

Other

Other2013 IEEE Biomedical Circuits and Systems Conference, BioCAS 2013
Country/TerritoryNetherlands
CityRotterdam
Period10/31/1311/2/13

ASJC Scopus subject areas

  • Hardware and Architecture
  • Biomedical Engineering
  • Electrical and Electronic Engineering

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