A clinician's guide to the diagnosis and treatment of interstitial lung diseases

Research output: Contribution to journalArticle

Abstract

Interstitial lung disease (ILD) is a final common pathway for a large number of lung insults. It is characterized by progressive scarring of the lung leading to restriction and diminished oxygen transfer. Clinically, the presenting symptoms of ILD are nonspecific (cough and progressive dyspnea on exertion) and are often attributed to other diseases, thus delaying diagnosis and timely therapy. ILD occurs most commonly in older individuals and is increasingly encountered by internists. Both the diagnosis and treatment can be daunting: patients frequently have irreversibly impaired lung function at diagnosis, and therapeutic modalities are limited and associated with significant adverse effects. This review will assist internists in the recognition and management of ILD, provide a benchmark for pulmonary referrals, and offer guidance in advising patients with this life-threatening disorder.

Original languageEnglish (US)
Pages (from-to)579-587
Number of pages9
JournalSouthern Medical Journal
Volume100
Issue number6
DOIs
StatePublished - Jun 2007

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Interstitial Lung Diseases
Lung
Benchmarking
Therapeutics
Cough
Dyspnea
Cicatrix
Referral and Consultation
Oxygen

Keywords

  • Cough
  • Dyspnea
  • ILD
  • Interstitial lung disease
  • Lung transplantation
  • Pulmonary fibrosis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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abstract = "Interstitial lung disease (ILD) is a final common pathway for a large number of lung insults. It is characterized by progressive scarring of the lung leading to restriction and diminished oxygen transfer. Clinically, the presenting symptoms of ILD are nonspecific (cough and progressive dyspnea on exertion) and are often attributed to other diseases, thus delaying diagnosis and timely therapy. ILD occurs most commonly in older individuals and is increasingly encountered by internists. Both the diagnosis and treatment can be daunting: patients frequently have irreversibly impaired lung function at diagnosis, and therapeutic modalities are limited and associated with significant adverse effects. This review will assist internists in the recognition and management of ILD, provide a benchmark for pulmonary referrals, and offer guidance in advising patients with this life-threatening disorder.",
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