A charge-deficient analogue of spermine with chelating properties

A. R. Khomutov, N. A. Grigorenko, S. G. Skuridin, A. V. Demin, J. Vepsalainen, Robert A Casero, P. M. Woster

Research output: Contribution to journalArticle

Abstract

1,12-Diamino-3,6,9-triazadodecane, a new isosteric and charge-deficient analogue of spermine, is synthesized. Unlike spermine, the new analogue is an excellent chelator of Cu2+ ions. Possible applications of this compound for studying enzymes of polyamine metabolism and cellular functions of spermine are discussed.

Original languageEnglish (US)
Pages (from-to)303-311
Number of pages9
JournalBioorganicheskaya Khimiya
Volume31
Issue number3
StatePublished - 2005

Fingerprint

Spermine
Chelation
Polyamines
Chelating Agents
Metabolism
Ions
Enzymes

Keywords

  • DNA
  • Polyamines
  • Spermine

ASJC Scopus subject areas

  • Organic Chemistry
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Khomutov, A. R., Grigorenko, N. A., Skuridin, S. G., Demin, A. V., Vepsalainen, J., Casero, R. A., & Woster, P. M. (2005). A charge-deficient analogue of spermine with chelating properties. Bioorganicheskaya Khimiya, 31(3), 303-311.

A charge-deficient analogue of spermine with chelating properties. / Khomutov, A. R.; Grigorenko, N. A.; Skuridin, S. G.; Demin, A. V.; Vepsalainen, J.; Casero, Robert A; Woster, P. M.

In: Bioorganicheskaya Khimiya, Vol. 31, No. 3, 2005, p. 303-311.

Research output: Contribution to journalArticle

Khomutov, AR, Grigorenko, NA, Skuridin, SG, Demin, AV, Vepsalainen, J, Casero, RA & Woster, PM 2005, 'A charge-deficient analogue of spermine with chelating properties', Bioorganicheskaya Khimiya, vol. 31, no. 3, pp. 303-311.
Khomutov AR, Grigorenko NA, Skuridin SG, Demin AV, Vepsalainen J, Casero RA et al. A charge-deficient analogue of spermine with chelating properties. Bioorganicheskaya Khimiya. 2005;31(3):303-311.
Khomutov, A. R. ; Grigorenko, N. A. ; Skuridin, S. G. ; Demin, A. V. ; Vepsalainen, J. ; Casero, Robert A ; Woster, P. M. / A charge-deficient analogue of spermine with chelating properties. In: Bioorganicheskaya Khimiya. 2005 ; Vol. 31, No. 3. pp. 303-311.
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