A case study of ICD-11 anatomy value set extraction from SNOMED CT

The 11th revision of the International Classification of Diseases (ICD-11) intends to derive its "ontological component" from external ontologies (e.g. SNOMED CT). One of the core value sets is an ICD-11 anatomy chapter. The objective of the present study is to develop and evaluate approaches to value set extraction from SNOMED CT for the ICD-11 anatomy use case. We investigated a number of resources comprising SNOMED CT base terms, the anatomical term mappings between ICD-0 (ICD for Oncology) and SNOMED CT. the CORE Problem List Subset of SNOMED CT, and the SNOMED CT stated form in Web Ontology Language (OWL). We used the Manchester OWL module extraction tool and its extension in Protege 4.1. We proposed and evaluated four semiautomatic value set extraction strategies based on different clinical contexts and discussed their implications in terms of domain coverage, granularity and clinical usefulness from both technical and clinical perspectives.