A case of postmenopausal androgen excess

Irene Lambrinoudaki; Nikos Dafnios; Agathi Kondi-Pafiti; Nikos Triantafyllou; Evangelia Karopoulou; Anastasia Papageorgiou; Areti Augoulea; Eleni Armeni; Maria Creatsa; Nikolaos Vlahos

doi:10.3109/09513590.2015.1075500

A case of postmenopausal androgen excess

Irene Lambrinoudaki, Nikos Dafnios, Agathi Kondi-Pafiti, Nikos Triantafyllou, Evangelia Karopoulou, Anastasia Papageorgiou, Areti Augoulea, Eleni Armeni, Maria Creatsa, Nikolaos Vlahos

Research output: Contribution to journal › Article

Abstract

Ovarian steroid cell tumors are very rare but potentially life-threatening neoplasms. They represent less than 0.1% of all ovarian tumors, typically present in premenopausal women and frequently manifest with virilization. Signs of hyperandrogenism may appear in postmenopausal women due to tumorus and non-tumorus adrenal and ovarian causes as well due to the normal aging process. In any case, steroid cell tumor should be suspected in postmenopausal women who present with rapid progressive androgen excess symptoms. This report describes a case of a 67-year-old postmenopausal woman with signs of hyperandrogenism, where an ovarian steroid cell tumor was diagnosed and treated by laparoscopic bilateral salpingo-oophorectomy and synchronous hysterectomy.

Original language	English (US)
Pages (from-to)	760-764
Number of pages	5
Journal	Gynecological Endocrinology
Volume	31
Issue number	10
DOIs	https://doi.org/10.3109/09513590.2015.1075500
State	Published - Oct 3 2015

Keywords

Androgen excess
ovarian tumor
postmenopause
salpingo-oophorectomy
virilization

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology
Obstetrics and Gynecology

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Lambrinoudaki, I., Dafnios, N., Kondi-Pafiti, A., Triantafyllou, N., Karopoulou, E., Papageorgiou, A., Augoulea, A., Armeni, E., Creatsa, M., & Vlahos, N. (2015). A case of postmenopausal androgen excess. Gynecological Endocrinology, 31(10), 760-764. https://doi.org/10.3109/09513590.2015.1075500

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title = "A case of postmenopausal androgen excess",

abstract = "Ovarian steroid cell tumors are very rare but potentially life-threatening neoplasms. They represent less than 0.1% of all ovarian tumors, typically present in premenopausal women and frequently manifest with virilization. Signs of hyperandrogenism may appear in postmenopausal women due to tumorus and non-tumorus adrenal and ovarian causes as well due to the normal aging process. In any case, steroid cell tumor should be suspected in postmenopausal women who present with rapid progressive androgen excess symptoms. This report describes a case of a 67-year-old postmenopausal woman with signs of hyperandrogenism, where an ovarian steroid cell tumor was diagnosed and treated by laparoscopic bilateral salpingo-oophorectomy and synchronous hysterectomy.",

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author = "Irene Lambrinoudaki and Nikos Dafnios and Agathi Kondi-Pafiti and Nikos Triantafyllou and Evangelia Karopoulou and Anastasia Papageorgiou and Areti Augoulea and Eleni Armeni and Maria Creatsa and Nikolaos Vlahos",

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AU - Lambrinoudaki, Irene

AU - Dafnios, Nikos

AU - Kondi-Pafiti, Agathi

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AU - Karopoulou, Evangelia

AU - Papageorgiou, Anastasia

AU - Augoulea, Areti

AU - Armeni, Eleni

AU - Creatsa, Maria

AU - Vlahos, Nikolaos

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AB - Ovarian steroid cell tumors are very rare but potentially life-threatening neoplasms. They represent less than 0.1% of all ovarian tumors, typically present in premenopausal women and frequently manifest with virilization. Signs of hyperandrogenism may appear in postmenopausal women due to tumorus and non-tumorus adrenal and ovarian causes as well due to the normal aging process. In any case, steroid cell tumor should be suspected in postmenopausal women who present with rapid progressive androgen excess symptoms. This report describes a case of a 67-year-old postmenopausal woman with signs of hyperandrogenism, where an ovarian steroid cell tumor was diagnosed and treated by laparoscopic bilateral salpingo-oophorectomy and synchronous hysterectomy.

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