A case of pityriasis rubra pilaris with associated focal acantholytic dyskeratosis complicated by Kaposi's varicelliform eruption

Gulsun Erdag, Deborah Lockman, Jennifer Tromberg, Thomas Cropley, James W. Patterson

Research output: Contribution to journalArticlepeer-review

Abstract

The clinical and histopathological diagnosis of pityriasis rubra pilaris (PRP) can be difficult because clinical findings are often subtle in early stages, and microscopic findings can overlap with those of other skin diseases. Focal acantholytic dyskeratosis (FAD) can rarely be seen in PRP and can mimic Darier's disease, Grover's disease or other disorders characterized by these histopathologic features. Kaposi's varicelliform eruption is a widespread infection due to herpes simplex virus (HSV) types 1 and 2, coxsackievirus A16 or vaccinia virus, occurring in a preexisting dermatosis; only one case has been reported in PRP. We report a patient with PRP whose biopsies showed both herpes simplex infection and FAD. A complete understanding of the mechanism behind this eruption evolved gradually, aided in great measure by the histopathologic findings.

Original languageEnglish (US)
Pages (from-to)919-922
Number of pages4
JournalJournal of Cutaneous Pathology
Volume38
Issue number11
DOIs
StatePublished - Nov 1 2011

Keywords

  • dermatopathology
  • pemphigus
  • skin

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology
  • Dermatology

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