A case of male pseudohermaphroditism associated with elevated LH, normal FSH and low testosterone possibly due to the secretion of an abnormal LH molecule

I. J. Park, L. S. Burnett, H. W. Jones, C. J. Migeon, R. M. Blizzard

Research output: Contribution to journalArticle

Abstract

A 27 yr old female is described who had 46,XY chromosome complement, ambiguous external genitalia with elevated LH, slightly above normal FSH and low testosterone. Her plasma testosterone level increased 15 to 20 fold after HCG stimulation (5000 IU x 3), then returned to prestimulation level 3 mth later. This was possibly due to the secretion of an abnormal LH molecule which is immunoreactive but biologically inactive in the human.

Original languageEnglish (US)
Pages (from-to)173-181
Number of pages9
JournalActa Endocrinologica
Volume83
Issue number1
StatePublished - 1976
Externally publishedYes

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XY Disorders of Sex Development 46
Testosterone
Disorders of Sex Development
Chromosomes

ASJC Scopus subject areas

  • Endocrinology

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A case of male pseudohermaphroditism associated with elevated LH, normal FSH and low testosterone possibly due to the secretion of an abnormal LH molecule. / Park, I. J.; Burnett, L. S.; Jones, H. W.; Migeon, C. J.; Blizzard, R. M.

In: Acta Endocrinologica, Vol. 83, No. 1, 1976, p. 173-181.

Research output: Contribution to journalArticle

Park, I. J. ; Burnett, L. S. ; Jones, H. W. ; Migeon, C. J. ; Blizzard, R. M. / A case of male pseudohermaphroditism associated with elevated LH, normal FSH and low testosterone possibly due to the secretion of an abnormal LH molecule. In: Acta Endocrinologica. 1976 ; Vol. 83, No. 1. pp. 173-181.
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