A case of combined central and peripheral demyelination in Zambia

Ilena C. George, Michelle Kvalsund, Deanna Saylor

Research output: Contribution to journalArticle

Abstract

Overlap syndromes, where otherwise distinct autoimmune processes of the central and peripheral nervous systems are present in the same patient, are uncommon and have not been previously reported in sub-Saharan Africa. We present a case of a 32-year-old man who was found to have both clinically isolated syndrome and chronic inflammatory demyelinating polyneuropathy, highlighting the importance of continued efforts to establish the prevalence of demyelinating disease in the region given the limited treatment options currently available for autoimmune disease.

Original languageEnglish (US)
Article number101943
JournalMultiple Sclerosis and Related Disorders
Volume40
DOIs
StatePublished - May 2020

Fingerprint

Zambia
Demyelinating Diseases
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Africa South of the Sahara
Peripheral Nervous System
Autoimmune Diseases
Central Nervous System
Therapeutics

Keywords

  • Autoimmune diseases
  • Chronic inflammatory demyelinating
  • Developing countries
  • Multiple sclerosis
  • Polyradiculoneuropathy
  • Undifferentiated connective tissue diseases

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

A case of combined central and peripheral demyelination in Zambia. / George, Ilena C.; Kvalsund, Michelle; Saylor, Deanna.

In: Multiple Sclerosis and Related Disorders, Vol. 40, 101943, 05.2020.

Research output: Contribution to journalArticle

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