A case of agnogenic myeloid metaplasia evolving into acute myelogenous leukemia associated with the development of trisomy 11 in bone marrow cells

C. V. Dang, P. H. Stein, D. R. Gress, G. A. Dallabetta, W. L. Bender

Research output: Contribution to journalArticle

Abstract

An 83-year-old woman who had a 5-year history of agnogenic myeloid metaplasia and a previous normal marrow cell karyotype presented with acute myelogenous leukemia (AML) associated with the development of trisomy 11 in 100% of cultured marrow cells. Isolated trisomy 11 in marrow cells has been reported previously in five cases of AML, suggesting that trisomy 11 is a nonrandom chromosomal aberration associated with AML.

Original languageEnglish (US)
Pages (from-to)285-288
Number of pages4
JournalAmerican Journal of Hematology
Volume19
Issue number3
DOIs
StatePublished - 1985

ASJC Scopus subject areas

  • Hematology

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