A case for immunization of human papillomavirus (HPV) 6/11-infected pregnant women with the quadrivalent HPV vaccine to prevent juvenile-onset laryngeal papilloma

Keerti V. Shah

Research output: Contribution to journalReview article

Abstract

Juvenile-onset recurrent respiratory papillomatosis (JORRP) is a rare disease caused by intrapartum or perinatal transmission of human papillomavirus (HPV) types 6 and 11 from an infected mother to the newborn. Immunization of a pregnant woman who has condyloma or HPV-6/11 infection with the quadrivalent HPV vaccine will result in a high neutralizing antibody response to HPV 6 and HPV 11 in her serum, and these antibodies transferred to the newborn will likely protect the child against the development of JORRP. Because of the low incidence of disease in at-risk children, it may be difficult to test the effectiveness of maternal immunization for prevention of JORRP.

Original languageEnglish (US)
Pages (from-to)1307-1309
Number of pages3
JournalJournal of Infectious Diseases
Volume209
Issue number9
DOIs
StatePublished - Jan 1 2014

Keywords

  • HPV
  • HPV 6/11
  • condyloma
  • immunization
  • pregnancy
  • respiratory papillomas

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases

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