A case-control study of risk factors for Haemophilus influenzae type b disease in Navajo children

Mark C. Wolff, Lawrence H. Moulton, Wendy Newcomer, Raymond Reid, Mathuram Santosham

Research output: Contribution to journalArticle

Abstract

To understand the potential risk factors and protective factors for invasive Haemophilus influenzae type b (Hib) disease, we conducted a case- control study among Navajo children less than two years of age resident on the Navajo Nation. We analyzed household interview data for 60 cases that occurred between August 1988 and February 1991, and for 116 controls matched by age, gender, and geographic location. The Hib vaccine recipients were excluded from the analyses. Conditional logistic regression models were fit to examine many variables relating to social and environmental conditions. Risk factors determined to be important were never breast fed (odds ratio [OR] = 3.55, 95% confidence interval [CI] = 1.52, 8.26), shared care with more than one child less than two years of age (OR = 2.32, 95% CI = 0.91, 5.96); wood heating (OR = 2.14, 95% CI = 0.91, 5.05); rodents in the home (OR = 8.18, 95% CI = 0.83, 80.7); and any livestock near the home (OR = 2.18, 95% CI = 0.94, 5.04).

Original languageEnglish (US)
Pages (from-to)263-266
Number of pages4
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume60
Issue number2
DOIs
StatePublished - Feb 1999
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology
  • Virology
  • Infectious Diseases

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