A Carcinoid Tumor in the Gallbladder of a Dog

C. N. Morrell; M. V. Volk; J. L. Mankowski

doi:10.1354/vp.39-6-756

A Carcinoid Tumor in the Gallbladder of a Dog

C. N. Morrell, M. V. Volk, J. L. Mankowski

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Abstract

A cholecystectomy was performed on a 10-year-old spayed female mixed-breed dog with chronic weight loss, persistently increased liver enzyme activities, and cholecystomegaly identified by ultrasonographic examination. A subsequent diagnosis of a biliary carcinoid was made based on a neuroendocrine-type histologic pattern, cytoplasmic argyrophilia by Grimelius staining, immunopositivity for chromogranin A, and the ultrastructural finding of cytoplasmic secretory granules in neoplastic cells. Extrahepatic biliary carcinoid tumors are rare tumors of humans and have not been documented in domestic animals.

Original language	English (US)
Pages (from-to)	756-758
Number of pages	3
Journal	Veterinary pathology
Volume	39
Issue number	6
DOIs	https://doi.org/10.1354/vp.39-6-756
State	Published - Nov 2002
Externally published	Yes

Keywords

Dogs
biliary
carcinoid
gallbladder

ASJC Scopus subject areas

veterinary(all)

Access to Document

10.1354/vp.39-6-756

Cite this

@article{9dc4ec77d2064ff8a722e2c13c03b75b,

title = "A Carcinoid Tumor in the Gallbladder of a Dog",

abstract = "A cholecystectomy was performed on a 10-year-old spayed female mixed-breed dog with chronic weight loss, persistently increased liver enzyme activities, and cholecystomegaly identified by ultrasonographic examination. A subsequent diagnosis of a biliary carcinoid was made based on a neuroendocrine-type histologic pattern, cytoplasmic argyrophilia by Grimelius staining, immunopositivity for chromogranin A, and the ultrastructural finding of cytoplasmic secretory granules in neoplastic cells. Extrahepatic biliary carcinoid tumors are rare tumors of humans and have not been documented in domestic animals.",

keywords = "Dogs, biliary, carcinoid, gallbladder",

author = "Morrell, {C. N.} and Volk, {M. V.} and Mankowski, {J. L.}",

note = "Funding Information: We would like to thank Dr. John D. Strandberg for assistance with electron microscopy and Mr. Fred Dubs for photography. This work was supported by NIH RR07002.",

year = "2002",

month = nov,

doi = "10.1354/vp.39-6-756",

language = "English (US)",

volume = "39",

pages = "756--758",

journal = "Pathologia veterinaria",

issn = "0300-9858",

publisher = "SAGE Publications Ltd",

number = "6",

}

TY - JOUR

T1 - A Carcinoid Tumor in the Gallbladder of a Dog

AU - Morrell, C. N.

AU - Volk, M. V.

AU - Mankowski, J. L.

N1 - Funding Information: We would like to thank Dr. John D. Strandberg for assistance with electron microscopy and Mr. Fred Dubs for photography. This work was supported by NIH RR07002.

PY - 2002/11

Y1 - 2002/11

N2 - A cholecystectomy was performed on a 10-year-old spayed female mixed-breed dog with chronic weight loss, persistently increased liver enzyme activities, and cholecystomegaly identified by ultrasonographic examination. A subsequent diagnosis of a biliary carcinoid was made based on a neuroendocrine-type histologic pattern, cytoplasmic argyrophilia by Grimelius staining, immunopositivity for chromogranin A, and the ultrastructural finding of cytoplasmic secretory granules in neoplastic cells. Extrahepatic biliary carcinoid tumors are rare tumors of humans and have not been documented in domestic animals.

AB - A cholecystectomy was performed on a 10-year-old spayed female mixed-breed dog with chronic weight loss, persistently increased liver enzyme activities, and cholecystomegaly identified by ultrasonographic examination. A subsequent diagnosis of a biliary carcinoid was made based on a neuroendocrine-type histologic pattern, cytoplasmic argyrophilia by Grimelius staining, immunopositivity for chromogranin A, and the ultrastructural finding of cytoplasmic secretory granules in neoplastic cells. Extrahepatic biliary carcinoid tumors are rare tumors of humans and have not been documented in domestic animals.

KW - Dogs

KW - biliary

KW - carcinoid

KW - gallbladder

UR - http://www.scopus.com/inward/record.url?scp=0036835481&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036835481&partnerID=8YFLogxK

U2 - 10.1354/vp.39-6-756

DO - 10.1354/vp.39-6-756

M3 - Article

C2 - 12450211

AN - SCOPUS:0036835481

SN - 0300-9858

VL - 39

SP - 756

EP - 758

JO - Pathologia veterinaria

JF - Pathologia veterinaria

IS - 6

ER -

A Carcinoid Tumor in the Gallbladder of a Dog

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this