A call to arms: The imperative for antimicrobial stewardship

Research output: Contribution to journalArticle

Abstract

Antimicrobial resistance is a major public health crisis. The prevalence of drug-resistant organisms, such as the emerging NAP1 strain of Clostridium difficile, now highly resistant to fluoroquinolones, Acinetobacter species, Klebsiella pneumoniae carbapenemase-producing organisms, and methicillin-resistant Staphylococcus aureus, is increasing nationwide. The sources of antimicrobial resistance are manifold, but there is a well-documented causal relationship between antimicrobial use and misuse and the emergence of antimicrobial-resistant pathogens. As the development of new antimicrobial agents is on the decline, the medical community, across all specialties and in conjunction with public health services, must develop and implement programs and strategies designed to preserve the integrity and effectiveness of the existing antimicrobial armamentarium. Such strategies are collectively known as antimicrobial stewardship programs and have the potential to minimize the emergence of resistant pathogens.

Original languageEnglish (US)
JournalClinical Infectious Diseases
Volume53
Issue numberSUPPL. 1
DOIs
StatePublished - Aug 15 2011

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Acinetobacter
United States Public Health Service
Clostridium difficile
Fluoroquinolones
Klebsiella pneumoniae
Methicillin-Resistant Staphylococcus aureus
Anti-Infective Agents
Public Health
Pharmaceutical Preparations
carbapenemase

ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology (medical)

Cite this

A call to arms : The imperative for antimicrobial stewardship. / Bartlett, John.

In: Clinical Infectious Diseases, Vol. 53, No. SUPPL. 1, 15.08.2011.

Research output: Contribution to journalArticle

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