TY - JOUR
T1 - A call to arms
T2 - The imperative for antimicrobial stewardship
AU - Bartlett, John G.
N1 - Funding Information:
Supplement sponsorship. This article was published as part of a supplement entitled ‘‘Antimicrobial Stewardship for the Community Hospital: Practical Tools and Techniques for Implementation,’’ jointly sponsored by the University of Cincinnati and Rockpointe Corporation, ACPE credit provided by Potomac Center for Medical Education, and supported by an educational grant from Ortho-McNeil. Potential conflict of interest. The author reported no conflicts.
PY - 2011/8/15
Y1 - 2011/8/15
N2 - Antimicrobial resistance is a major public health crisis. The prevalence of drug-resistant organisms, such as the emerging NAP1 strain of Clostridium difficile, now highly resistant to fluoroquinolones, Acinetobacter species, Klebsiella pneumoniae carbapenemase-producing organisms, and methicillin-resistant Staphylococcus aureus, is increasing nationwide. The sources of antimicrobial resistance are manifold, but there is a well-documented causal relationship between antimicrobial use and misuse and the emergence of antimicrobial-resistant pathogens. As the development of new antimicrobial agents is on the decline, the medical community, across all specialties and in conjunction with public health services, must develop and implement programs and strategies designed to preserve the integrity and effectiveness of the existing antimicrobial armamentarium. Such strategies are collectively known as antimicrobial stewardship programs and have the potential to minimize the emergence of resistant pathogens.
AB - Antimicrobial resistance is a major public health crisis. The prevalence of drug-resistant organisms, such as the emerging NAP1 strain of Clostridium difficile, now highly resistant to fluoroquinolones, Acinetobacter species, Klebsiella pneumoniae carbapenemase-producing organisms, and methicillin-resistant Staphylococcus aureus, is increasing nationwide. The sources of antimicrobial resistance are manifold, but there is a well-documented causal relationship between antimicrobial use and misuse and the emergence of antimicrobial-resistant pathogens. As the development of new antimicrobial agents is on the decline, the medical community, across all specialties and in conjunction with public health services, must develop and implement programs and strategies designed to preserve the integrity and effectiveness of the existing antimicrobial armamentarium. Such strategies are collectively known as antimicrobial stewardship programs and have the potential to minimize the emergence of resistant pathogens.
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U2 - 10.1093/cid/cir362
DO - 10.1093/cid/cir362
M3 - Article
C2 - 21795727
AN - SCOPUS:79960976033
SN - 1058-4838
VL - 53
SP - S4-S7
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
IS - SUPPL. 1
ER -